Solution
from flask import render_template, send_file
from io import BytesIO
from zipfile import ZipFile
# ...
@app.route('/download')
def download():
output = { 'name': 'Unknown' }
result_html = render_template('result.html', **output)
stream = BytesIO()
with ZipFile(stream, 'w') as zf:
zf.writestr('result.html', result_html)
# ...
stream.seek(0)
return send_file(stream, as_attachment=True, attachment_filename='archive.zip')