Solution
@app.route('/playlist', methods=['GET', 'POST'])
def create_playlist():
resp = spotify.authorized_response()
session['oauth_token'] = (resp['access_token'], '')
username = USER
return spotify.post('https://api.spotify.com/v1/users/' + username + '/playlists',
data={'name': 'playlist_name', 'description': 'something'}, format='json')